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Key benefits of GEiGS^®

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  Precise, predictable, and stable tuning of target gene expression

  By redirecting the silencing activity of the host’s own non-coding genes, GEiGS^® introduces novel RNAi activity with highly programmable potency and tissue specificity. This elegant approach requires only minimal changes to the host’s genome (less than 20 nucleotides), thus avoiding transcriptional gene silencing and allowing for highly stable RNAi activity over time and across generations.

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  Accelerated development of critical disease and pest resistance traits

  GEiGS^® can be used to redirect the silencing activity of the host’s native non-coding genes towards well characterized and highly conserved viral, fungal or pest genes. This distinctly direct approach significantly accelerates product development time while minimizing pleiotropic effects associated with editing the host’s coding genes.

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  Favourable regulatory classification in multiple markets

  GEiGS^® technology does not involve the insertion of DNA sequences from other organisms (‘Foreign DNA’) into the host genome and does not impact the sequence of proteins. These factors allow for a non-GM classification in multiple major markets and a more streamlined regulatory approval process.

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  Universal platform that works with existing gene editing tools

  GEiGS^® is not dependent on any one specific gene editing tool, but instead can be deployed by using a broad range of different nucleases. This provides the user with freedom to choose which gene editing tools they use to implement GEiGS^® edits – tools that may already be applied in their existing pipelines.