GEiGS® uses universal gene editing tools such as CRISPR, to minimally edit the host’s own non-coding genes and redirect their silencing activity (RNAi) towards any desired target gene or gene family.
GEiGS-BioCompute is the cutting edge bioinformatics platform that designs gene editing solutions to allow precise and effective implementation of GEiGS® technology.
By redirecting the silencing activity of the host’s own non-coding genes, GEiGS® introduces novel RNAi activity with highly programmable potency and tissue specificity. This elegant approach requires only minimal changes to the host’s genome (less than 20 nucleotides), thus avoiding transcriptional gene silencing and allowing for highly stable RNAi activity over time and across generations.
GEiGS® can be used to redirect the silencing activity of the host’s native non-coding genes towards well characterized and highly conserved viral, fungal or pest genes. This distinctly direct approach significantly accelerates product development time while minimizing pleiotropic effects associated with editing the host’s coding genes.
GEiGS® technology does not involve the insertion of DNA sequences from other organisms (‘Foreign DNA’) into the host genome and does not impact the sequence of proteins. These factors allow for a non-GM classification in multiple major markets and a more streamlined regulatory approval process.
GEiGS® is not dependent on any one specific gene editing tool, but instead can be deployed by using a broad range of different nucleases. This provides the user with freedom to choose which gene editing tools they use to implement GEiGS® edits – tools that may already be applied in their existing pipelines.
Find out how GEiGS® technology can benefit you
We collaborate with world-leading companies and academic institutions, enabling them to access our pioneering GEiGS® technology to address some of the most pressing agricultural production challenges.
Contact us today to discuss GEiGS® licensing and service options and join us in driving innovation forward.
geigs@tropic.bio +44 (0)1603 274441
Tropic Announces Collaboration with Corteva Agriscience Utilizing Tropic’s Groundbreaking GEiGS® Technology to Develop Robust Disease Resistance Traits in Corn and Soybean
Tropic’s non-browning gene-edited banana cleared for production in the Philippines
British Sugar and Tropic announce strategic collaboration to sustainably tackle devastating disease of sugar beet
Genus Plc and Tropic announce extension and expansion of trait development collaboration
Positive response from USDA on regulatory status using GEiGS®
eggXYt licenses GEiGS® to develop avian flu resistance in chickens
Genus plc announces strategic GEiGS® collaboration
BASF to utilize ground-breaking GEiGS® technology to develop traits
Tropic Biosciences launches breakthrough GEiGS® platform Tropic Announces Collaboration with Corteva Agriscience Utilizing Tropic’s Groundbreaking GEiGS® Technology to Develop Robust Disease Resistance Traits in Corn and Soybean Tropic’s non-browning gene-edited banana cleared for production in the Philippines British Sugar and Tropic announce strategic collaboration to sustainably tackle devastating disease of sugar beet Genus Plc and Tropic announce extension and expansion of trait development collaboration Positive response from USDA on regulatory status using GEiGS® eggXYt licenses GEiGS® to develop avian flu resistance in chickens Genus plc announces strategic GEiGS® collaboration BASF to utilize ground-breaking GEiGS® technology to develop traits Tropic Biosciences launches breakthrough GEiGS® platform
Gene Editing induced Gene Silencing
from Tropic
